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Sarbani Bhaduri, M.D., Joins Acologix as Vice President, Medical Affairs

Hayward, CA – September 12, 2005 – Acologix, Inc. a privately held biopharmaceutical company, today announced the appointment of Sarbani Bhaduri, M.D. as its Vice President of Medical Affairs. As a board certified nephrologist and with her experiences in early to late stage clinical development, Dr. Bhaduri brings substantial expertise in therapeutic product development for osteo-renal diseases.

Prior to joining Acologix, Dr. Bhaduri was the Nephrology Franchise Associate Medical Director for Ortho Biotech, a subsidiary company of Johnson and Johnson. At Ortho Biotech, Dr. Bhaduri was responsible for Phase II, III, and IV clinical development using Epoetin alfa. Dr. Bhaduri was part of the leadership team on the Phase I and II clinical research investigating BMP-7, a bone morphogenetic protein which may be useful in the prevention of kidney fibrosis.

Prior to joining Ortho Biotech, Dr. Bhaduri served as the Division Head of Nephrology and Medical Director of Kidney/Pancreas Transplantation at Scripps Clinic and Research Institute. Prior to joining Scripps, Dr. Bhaduri was an Assistant Professor of Internal Medicine at the University of California San Francisco and Davis for a total of five years. Dr. Bhaduri received her B.S. from University of Texas at El Paso and her M.D. at Texas Tech University, School of Medicine.

Dr. Bhaduri has also published numerous papers in the field of anemia associated with chronic kidney disease, and kidney transplantation as related to transplant sensitization and tolerance.

“We are thrilled to have Dr. Bhaduri join our team,” said Yoshi Kumagai, President and CEO of Acologix. He added, “We found that Dr. Bhaduri was not only a highly experienced clinician but also an excellent scientist who had a profound understanding of osteo-renal physiology. With Acologix now entering middle to late stage clinical development for several of our development products, Dr. Bhaduri’s addition to the team completes our in-house product development capabilities for the foreseeable future.”

About Acologix, Inc.

Acologix strives to improve patients’ lives by developing and commercializing innovative biopharmaceuticals targeting “osteo-renal” (bone and kidney) diseases. Acologix’s substantial expertise in identifying and developing therapeutics with unique mechanisms of action (such as mineral metabolism sciences) is key to solving major kidney and bone health problems. Chronic kidney failure, renal osteodystrophy, orthopedics, periodontal disease, general dentistry and oral care represent significant underserved medical needs. Acologix is unique in its focus on these rapidly growing health care problems. Acologix has recently announced the partnership with Toray Industries, Inc. of Japan on the development and commercialization of AC-820, an anti-puritic agent for the treatment of uremic pruritus in dialysis patients. Pivotal Phase III clinical studies are expected to start in Europe and the US in late 2005 and 2006, respectively. Acologix’s leading skeletal tissue regenerating compound, AC-100 (Dentonin®) is currently undergoing two Phase II clinical studies in Europe and the United States for the repair of periodontal defects and in dental restorations, respectively. Acologix is also developing Phosphatonin to treat hyperphosphatemia and its subsequent clinical problems in chronic kidney disease.

This press release contains “forward-looking” statements. These statements involve risks and uncertainties, which may cause results to differ materially from those set forth in the statements. The forward-looking statements include statements regarding product development and cannot be guaranteed. Acologix undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events, or otherwise. Forward-looking statements in this press release should be evaluated together with the many uncertainties that affect Acologix’s business.

Company Contact

Yoshi Kumagai
President and CEO
Phone: 510.512.7200
Fax: 510.786.1116
ir@acologix.com


     
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